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Long-term oral contraceptive users twice as likely to have serious eye disease


Nov. 18, 2013 — Analysis offered lately, on the 117th Annual Assembly of the American Academy of Ophthalmology in New Orleans, has discovered that girls who’ve taken oral contraceptives for 3 or extra years are twice as prone to endure from glaucoma, some of the top reasons of blindness which impacts virtually 60 million international. The researchers warning gynecologists and ophthalmologists to pay attention to the truth that oral contraceptives would possibly play a job in glaucomatous illnesses, and inform sufferers to have their eyes screened for glaucoma if additionally they produce other possibility components.

The find out about — performed through researchers at College of California, San Francisco, Duke College Faculty of Drugs and 1/3 Affiliated Sanatorium of Nanchang College, Nanchang, China — is the primary to determine an elevated chance of glaucoma in ladies who’ve used oral contraceptives for 3 or extra years. The researchers utilized 2005-2008 knowledge from the Nationwide Well being and Diet Examination Survey (NHANES), administered by means of the Facilities for Illness Keep watch over, which integrated three,406 feminine members aged forty years or older from throughout the USA who achieved the survey’s imaginative and prescient and reproductive well being questionnaire and underwent eye assessments. It discovered that women who had used oral contraceptives, regardless of which sort, for longer than three years are 2.05 occasions extra more likely to additionally file that they have got the prognosis of glaucoma.

Even if the consequences of the learn about don’t talk immediately to the causative impact of oral contraceptives on the improvement of glaucoma, it signifies that lengthy-time period use of oral contraceptives may well be a possible chance issue for glaucoma, and could also be regarded as as a part of the danger profile for a affected person at the side of different present chance components. These embody components corresponding to African American- ethnicity, domestic historical past of glaucoma, historical past of elevated eye force or current field of vision defects. Earlier research within the box have proven that estrogen may just play a major function within the pathogenesis of glaucoma.

“This learn about will have to be an impetus for future analysis to show the lead to and impact of oral contraceptives and glaucoma,” stated Shan Lin, M.D., lead researcher and professor of medical ophthalmology on the College of California San Francisco. “At this level, girls who’ve taken oral contraceptives for 3 or extra years must be screened for glaucoma and adopted intently by using an ophthalmologist, particularly if they’ve another present possibility elements.”

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